Heparan sulfates (HSs) are the main components in the glycocalyx which covers endothelial cells and modulates vascular homeostasis through interactions with multiple Heparan sulfate binding proteins (HSBPs). During sepsis. heparanase increases and induces HS shedding. The process causes glycocalyx degradation. https://www.nacrack.com/amazing-offer-Grand-Love-Reposado-Tequila-Red-Glass-Heart-save-extra/