Abstract ETS2 repressor factor (ERF) is a member of the ETS family of transcriptional repressors downstream of ERK. Although germline truncated variants in ERF have been identified in individuals with Noonan-like syndrome with or without craniosynostosis. the clinical spectrum of ERF variant-positive individuals and the functional characterization of ERF variants are currently not ful... https://www.rawafricaonline.com/