BackgroundThe epithelium in the colonic mucosa is implicated in the pathophysiology of various diseases. including inflammatory bowel diseases and colorectal cancer. Intestinal epithelial organoids from the colon (colonoids) can be used for disease modeling and personalized drug screening. Colonoids are usually cultured at 18-21% oxygen without accounting for the physiological hypoxia... https://www.getpureroutine.com/